Stemming Our Irrational Exuberance

Brenner, Malcolm K.
August 2011
Molecular Therapy;Aug2011, Vol. 19 Issue 8, p1399
Academic Journal
The author reflects on the technique to generate human embryonic stem cells (hESCs) and inducible pluripotent stem cells (iPSCs). He says that hESCs and iPSCs are genetically modified and has a major benefit for almost every disease. An overview of the argument regarding the bond issue for the establishment of the California Institute for Regenerative Medicine is offered. The author stresses the need to emphasize stem cell research to increase the safety of approaches using stem cell therapy.


Related Articles

  • A Comparison of Stem Cells for Therapeutic Use. Rodgerson, Denis; Harris, Alan // Stem Cell Reviews & Reports;Dec2011, Vol. 7 Issue 4, p782 

    A critical comparison of the attributes of several types of stem cells is presented, with particular emphasis on properties that are critical for the application of these cells for therapeutic purposes. The importance of an autologous source of pluripotent stem cells is stressed. It is apparent...

  • Senescence suppressors: their practical importance in replicative lifespan extension in stem cells. Hwang, Eun // Cellular & Molecular Life Sciences;Nov2014, Vol. 71 Issue 21, p4207 

    Recent animal and clinical studies report promising results for the therapeutic utilization of stem cells in regenerative medicine. Mesenchymal stem cells (MSCs), with their pluripotent nature, have advantages over embryonic stem cells in terms of their availability and feasibility. However,...

  • Personalized Regenerative Medicine. Arjmand, Babak; Goodarzi, Parisa; Mohamadi-Jahani, Fereshteh; Falahzadeh, Khadijeh; Larijani, Bagher // Acta Medica Iranica;2017, Vol. 55 Issue 3, p144 

    Personalized medicine as a novel field of medicine refers to the prescription of specific therapeutics procedure for an individual. This approach has established based on pharmacogenetic and pharmacogenomic information and data. The terms precision and personalized medicines are sometimes...

  • Keeping an eye on stem cells for studying disease modelling and cell-based therapy. Crombie, Duncan // Australasian Biotechnology;Mar2013, Vol. 23 Issue 1, p19 

    The article discusses the use of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) in treating eye-related diseases. Topics featured in the discussion include regenerative medicine, cell differentiation, and stem cell-based therapy. It mentions the Centre for Eye Research...

  • Amniotic fluid stem cells: an ideal resource for therapeutic application in bone tissue engineering. PANTALONE, A.; ANTONUCCI, I.; GUELFI, M.; PANTALONE, P.; USUELLI, F. G.; STUPPIA, L.; SALINI, V. // European Review for Medical & Pharmacological Sciences;Jul2016, Vol. 20 Issue 13, p2884 

    OBJECTIVE: Skeletal diseases, both degenerative and secondary to trauma, infections or tumors, represent an ideal target for regenerative medicine and in the last years, stem cells have been considered as good candidates for in vitro and in vivo bone regeneration. To date, several stem cell...

  • DNp73 improves generation efficiency of human induced pluripotent stem cells.  // BMC Cell Biology;2012, Vol. 13 Issue 1, p9 

    The article focuses on the research article presented by Yi Lin and colleagues on the NH2-terminally truncated p73 (DNp73) that helps in improving the efficiency of human induced pluripotent stem cells. It mentions that the human induced pluripotent stem cells are used in regenerative medicine,...

  • Stem cell therapy: A novel & futuristic treatment modality for disaster injuries. Gurudutta, G. U.; Satija, Neeraj Kumar; Singh, Vimal Kishor; Verma, Yogesh Kumar; Gupta, Pallavi; Tripathi, R. P // Indian Journal of Medical Research;Jan2012, Vol. 135 Issue 1, p15 

    Stem cell therapy hold the potential to meet the demand for transplant cells/tissues needed for treating damages resulting from both natural and man-made disasters. Pluripotency makes embryonic stem cells and induced pluripotent stem cells ideal for use, but their teratogenic character is a...

  • Gene interaction studies in cellular reprogramming of adult stem cells to embyronic like stem cells. Gangadaran, Nishanthi; James, Jannet Vennila // Bioinformation;2012, Vol. 8 Issue 19, p912 

    The sophisticated process of reprogramming of adult stem cells to embryonic-like stem cells, known as cellular reprogramming, involves the risk of generation of tumorigenic cells due to the complexity involved. Oct4 protein is the inevitable element for inducing pluripotency along with Sox2 and...

  • Electrically Guiding Migration of Human Induced Pluripotent Stem Cells. Zhang, Jiaping; Calafiore, Marco; Zeng, Qunli; Zhang, Xiuzhen; Huang, Yuesheng; Li, Ronald; Deng, Wenbin; Zhao, Min // Stem Cell Reviews & Reports;Dec2011, Vol. 7 Issue 4, p987 

    A major road-block in stem cell therapy is the poor homing and integration of transplanted stem cells with the targeted host tissue. Human induced pluripotent stem (hiPS) cells are considered an excellent alternative to embryonic stem (ES) cells and we tested the feasibility of using small,...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics