TITLE

Marine Drugs Acting as Autophagy Modulators

AUTHOR(S)
Dyshlovoy, Sergey A.; Honecker, Friedemann
PUB. DATE
January 2020
SOURCE
Marine Drugs;Jan2020, Vol. 18 Issue 1, p53
SOURCE TYPE
Academic Journal
DOC. TYPE
Editorial
ABSTRACT
Autophagy (Ancient Greek [ I autóphagos i ] - "self-devouring") is defined as a regulated mechanism of the degradation of unnecessary or dysfunctional cellular components [[1]]. Although it can be considered a basic catabolic process, autophagy has only recently become the focus of dedicated research. Its aim is to cover the whole scope of agents with autophagy-modulating activity, from novel to previously characterized, including already clinically used marine-derived compounds known to target autophagy both in vitro and in vivo. The issue will present work on compounds that are able to modulate all the different types of autophagy, i.e., macroautophagy, microautophagy, and chaperone-mediated autophagy, with cytotoxic, cytoprotective, pro-survival, or non-cytotoxic biological activity.
ACCESSION #
141410871

 

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