TITLE

The effect of polyherbal formulation DIA7 on fasting blood glucose level in alloxan induced diabetic rats

AUTHOR(S)
Mohammed Muneersha T. K.; Fathima Habeeba T. E.; Musambil, Mohthash; Mirshad P. V.; Fasalu Rahiman O. M.; Vasudevan M.
PUB. DATE
December 2014
SOURCE
Der Pharma Chemica;2014, Vol. 6 Issue 5, p215
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Many plants are found to be effective in the management of lifestyle diseases, there is an increased focus on herbal medicines in recent times. DIA7 is the Polyherbal formulation containing multiple ingredients of herbal origin, which are individually used in traditional system of medicine in the treatment of various metabolic disorders including Diabetic Mellitus. DIA7 consists of seven medicinal plants namely Salacia reticilata, Aegle marmelose, Azadirachta indica, Curcuma longa, Trigonella foenum graecum, Nigella sativa and Embilica officinalis. The above dried ingredients were powdered and formulated as DIA7 and administered orally to the animals by suspending in 0.5% Carboxy Methyl Cellulose solution. The effect of the Polyherbal Formulation DIA7 on fasting blood glucose level was evaluated by treatment with three dose levels i.e. 100, 200 and 400 mg/kg/day orally in both Alloxan induced diabetic rats for 28 days. From the study, DIA7 was found to be very effective in control of fasting blood glucose level in Alloxan induced diabetic rats, at a dose level of 400 mg/kg. The study indicates that the various active principles in DIA7 had produced a combined effect on fasting blood sugar level of the experimental rats.
ACCESSION #
99397425

 

Related Articles

  • Stachys lavandulifolia Vahl. and its Relation With Marmazad Activities in Traditional Manuscripts. Minae, Bagher; Sardari, Mehdi; Sharifi, Hossein; Rahim Abadi, Massih Sedigh; Sadeghpour, Omid // Iranian Red Crescent Medical Journal;Nov2015, Vol. 17 Issue 11, p1 

    Context: In modern phytotherapy, Stachys lavandulifolia Vahl., a type of Stachys also known as Mountain Tea (Chay-e-Kouhi) has been widely studied based on its botanical and therapeutic characteristics over the recent decades. Evidence Acquisition: The present study investigated morphology,...

  • The Effect of Berchemia berchemiaefolia Extract in a Rat Model Acetic Acid-induced Irritable Bowel Syndrome. Gilhyun Lee; Junseon Lee; Miha Joo; Seokcheol Choi; Kyungyae Hyun // International Journal of Bio-Science & Bio-Technology;2014, Vol. 6 Issue 5, p67 

    This study was conducted to reveal medicinal effect of Berchemia berchemiaefolia (BB) extract for induced IBS-rat model. IBS was induced by injecting acetic acid into target of Spraque-Dawley rats' colon. Control group and experimental group were categorized as follows; Group I: control group...

  • EFFICACY OF GYMNEMA SYLVESTRE IN ALLEVIATION OF STREPTOZOTOCIN INDUCED DIABETES IN RATS. Mallikarjuna, G.; Rao, Suguna; Shridhar, N. B.; Sathyanarayana, M. L.; Byregowda, S. M.; Ravikumar, P. // International Journal of Advanced Biological Research;2013, Vol. 3 Issue 1, p51 

    A hydroalcoholic extract of Gymnema sylvestre leaves (100 mg/kg b w / day) was tested for its biochemical and pathomorphological effects in streptozotocin induced diabetes in rats. Streptozotocin produced diabetes effectively in all the animals at 45 mg/kg in citrate buffer intraperitonially...

  • Comparative Research of Six Kinds of Callicarpa Medicinal Herbs in the Character Identification, Semi-microscopic Identification and Microscopic Identification. Yanxiang QIU; Man CAO; Danyan ZHANG; Wei MO // Medicinal Plant;Aug2015, Vol. 6 Issue 7/8, p1 

    [Objective] To establish a simple and easy identification method for six kinds of Callicarpa medicinal herbs, to ensure the clinical medication safety, and to provide references for the quality control of Callicarpa medicinal herbs. [Methods] Character identification, semi-microscopic...

  • Constituents of Essential Oils from Amomum longiligulare from Vietnam. Chau, Le; Thang, Tran; Huong, Le; Ogunwande, Isiaka // Chemistry of Natural Compounds;Nov2015, Vol. 51 Issue 6, p1181 

    The article discusses a study which examined the constituents of essential oils from Amomum longiligulare, a medicinal plant from Vietnam. Cited are some diseases treated by the medicinal plant including indigestion, abdominal burn cold, diarrhea, threatened abortion, dysentery, toothache and...

  • Increased 5-HT Levels Following Repeated Administration of Nigella sativa L. (Black Seed) Oil Produce Antidepressant Effects in Rats. PERVEEN, Tahira; HAIDER, Saida; ZUBERI, Nudrat Anwar; SALEEM, Sadia; SADAF, Sana; BATOOL, Zehra // Scientia Pharmaceutica;Jan-Mar2014, Vol. 82 Issue 1, p161 

    The seeds of Nigella sativa L., commonly known as black seed or black cumin, and its extracts are used in folk medicine in the Middle East and in Asian countries for the promotion of good health and as a remedy for many ailments. These seeds have many acclaimed medicinal properties such as...

  • The Effect of Butylphthalide on the Brain Edema, Blood-Brain Barrier of Rats After Focal Cerebral Infarction and the Expression of Rho A. Hu, Jinyang; Wen, Qingping; Wu, Yue; Li, Baozhu; Gao, Peng // Cell Biochemistry & Biophysics;Jun2014, Vol. 69 Issue 2, p363 

    The aim of this study was to explore the effect of butylphthalide on the brain edema, blood-brain barrier of rats of rats after focal cerebral infarction and the expression of Rho A. A total of 195 sprague-dawley male rats were randomly divided into control group, model group, and butylphthalide...

  • Protective effect of senegenin on splenectomy-induced postoperative cognitive dysfunction in elderly rats. LUYUAN YU; LEI SUN; SULI CHEN // Experimental & Therapeutic Medicine;2014, Vol. 7 Issue 4, p821 

    Postoperative cognitive dysfunction (POCD) is common in elderly patients. Senegenin, an active component of extracts from Polygala tenuifolia root, a traditional Chinese medicine, has neuroprotective and neuroregenerative effects. However, the mechanism underlying the effects of senegenin...

  • Medicinal Plants in the Treatment of Diabetes Mellitus. Hosseini, Seyed Ebrahim; Tavakoli, Farnaz; Karami, Mohammad // Journal of Clinical Excellence;2014, Vol. 2 Issue 2, p64 

    Diabetes Melitus is a complex disease. For most people, it's a new way of life, and it affects relationships in all areas as much as it affects eating and physical activity. If blood sugar level remains consistently higher than normal, over time it can make dameges on organs like heart, eyes,...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics