Establishment and experimental study of alveolar preservation before dental implantation in Beagle dogs

HAN Xue-song; LI Xiu-juan; HUANG Yuan-liang; ZHU Guo-guang; YOU Su-lan; TAN Luan-jun
February 2013
Shanghai Journal of Stomatology;Feb2013, Vol. 22 Issue 1, p46
Academic Journal
PURPOSE: To establish the model of alveolar ridge preservation after tooth extraction for dental implant replacement, and to observe the effect of tissue engineered bone on osseointegration. METHODS: Isolated BMSCs were expanded and osteogenically induced in vitro. The tissue engineering complex was constructed with BMSCs/A-PCPC in vitro. Six extraction sockets, with three on each side, were created in the mandibles of four Beagle dogs by extracting the second, third and fourth premolars. BMSCs/A-PCPC were placed on one side of the extraction sockets, while autogenous bone, A-PCPC and nothing were placed on the other side as control. X-ray and CT scans were conducted 1day, 4 and 12 weeks after operation to detect the change of the alveolar ridge. The bone of sockets were harvested at 8-week post-implantation and subject to histological for evaluating. SPSS17.0 software package was used for data analysis. RESULTS: Radiographs demonstrated higher radiodensity in group of complex than in simple materials group, autogenous bone group after 4 weeks. Hard tissue biopsy at 12-week showed that bone activity of BMSCs/A-PCPC complex was better than the other groups. Spiral CT analysis showed that alveolar ridge of each group experienced a certain degree of absorption. At 12-week, the alveolar ridge height reduction values in A-PCPC group was smaller than in A-PCPC group, autogenous bone group and blank group (P<0.05). CONCLUSION: The BMSCs/A-PCPC complex is favorable for preservation of alveolar ridge.


Related Articles

  • Endosseous Implants in Horizontal Alveolar Ridge Distraction Osteogenesis. Nosaka, Yasuhiro; Kitano, Saki; Wada, Keinoshin; Komori, Takahide // International Journal of Oral & Maxillofacial Implants;Nov/Dec2002, Vol. 17 Issue 6, p846 

    Purpose: This study evaluated horizontal distraction of the narrow alveolar ridge in dogs and the possibility of achieving osseointegration of implants placed into the distracted site during a consolidation period. Materials and Methods: Six beagle dogs weighing approximately 9 to 10 kg were...

  • Experimental study on osteoinduction active material in repairing the peri-implant bone defect. ZHAO Wang; WANG Qiu-xu; LIU Wei-xian // Shanghai Journal of Stomatology;Apr2009, Vol. 18 Issue 2, p189 

    PURPOSE: To explore the potential of using osteoinduction active material (OAM) for reconstruction of bone defects of peri-implant by animal experiment, and provide experimental evidence for clinical application. METHODS: Four Beagle dogs underwent extraction of the mandibular first and second...

  • Comparative evaluation of various methods of assessing residual alveolar ridge width prior to dental implant placement: An in vivo study. Sutaria, F; Shah, D; Chauhan, C; Solanki, J; Bhatti, K // Journal of Dental Implants;Jan-Jun2019, Vol. 9 Issue 1, p12 

    Purpose: There is always a slow but steady evolution occurred in dentistry, resulting in use of osseointegrated dental implants which became widely accepted procedure in the rehabilitation of edentulous spaces. Evaluation of the available alveolar bone dimensions is an important prerequisite for...

  • Histomorphometric Study of Ion Implantation and Diamond-like Carbon as Dental Implant Surface Treatments in Beagle Dogs. De Maeztu, Miguel A.; Braceras, Iñigo; Iñaki^Alava, J.; Sánchez-Garcés, M. Angeles; Gay-Escoda, Cosme // International Journal of Oral & Maxillofacial Implants;Mar/Apr2007, Vol. 22 Issue 2, p273 

    Purpose: Improvements in the bone-implant interface can provide clinical benefits, such as increasing the amount of bone in contact with the implant and shortening the time required to achieve sufficient bone appositioning to allow early prosthetic loading. The present study describes the...

  • Ridge Augmentation Using Mandibular Block Bone Grafts: Preliminary Results of an Ongoing Prospective Study. Sethi, Ashok; Thomas Kaus // International Journal of Oral & Maxillofacial Implants;May/Jun2001, Vol. 16 Issue 3, p378 

    The aim of the current ongoing study is to evaluate the long-term results of endosseous implants placed into autogenous bone grafts from intraoral donor sites. Patient selection for the correction of bone deficiencies was based on biomechanical and esthetic needs. Donor site selection was...

  • Ridge Mapping for Determination of Alveolar Ridge Width. Wilson, David J. // International Journal of Oral & Maxillofacial Implants;Spring1989, Vol. 4 Issue 1, p94 

    Ridge mapping is a measurement procedure to ensure that the diameter of an endosseous screw implant does not exceed the dimensions of available bone. The long-term success of implants is a prime aim. To achieve this, it is essential for the initial evaluation of the dimensions of the resorbing...

  • Experimental Alveolar Ridge Augmentation by Distraction Osteogenesis Using a Simple Device that Permits Secondary Implant Placement. Oda, Tomoo; Sawaki, Yoshihiro; Ueda, Minoru // International Journal of Oral & Maxillofacial Implants;Jan/Feb2000, Vol. 15 Issue 1, p95 

    The purpose of this study was to develop an improved technique of alveolar ridge augmentation by distraction osteogenesis using distraction screws, and to investigate tissue reactions to titanium implants at the distraction site. The left mandibular premolars were extracted from 6 adult dogs....

  • Lateral Augmentation of the Maxilla and Mandible Using Framework Technique With Allogeneic Bone Grafts. Wallowy, Phillip; Dorow, Andreas // Journal of Oral Implantology;2012, Vol. 38 Issue 6, p661 

    This study aimed to evaluate the effectiveness of lateral ridge augmentation in 36 patients with severely atrophic alveolar ridge using allogeneic bone grafts in a framework technique. A thinned allogeneic cortical graft was screwed to the alveolar ridge, leaving a hollow space that was filled...

  • Clinical application of alveolar ridge augment of posterior mandible using modified sandwich technique with immediate implantations. GUO Zhao-zhong; ZHANG Heng; ZHOU Ting-ting; YANG Xu; LIU Xue; WU Jia-bao // Shanghai Journal of Stomatology;Apr2013, Vol. 22 Issue 2, p210 

    PURPOSE: To evaluate the clinical values of alveolar ridge augment of atrophic posterior mandible using modified sandwich technique with immediate implantations. METHODS: Three patients with atrophic posterior mandible were enrolled in this study. A sandwich osteotomy was performed using a...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics