TITLE

Safety and efficacy of personal care products containing colloidal oatmeal

AUTHOR(S)
Criquet, Maryline; Roure, Romain; Dayan, Liliane; Nollent, Virginie; Bertin, Christiane
PUB. DATE
December 2012
SOURCE
Clinical, Cosmetic & Investigational Dermatology;2012 Part 2, Vol. 5, p183
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: Colloidal oatmeal is a natural ingredient used in the formulation of a range of personal care products for relief of skin dryness and itchiness. It is also used as an adjunctive product in atopic dermatitis. The safety of personal care products used on vulnerable skin is of particular importance and the risk of developing further skin irritations and/or allergies should be minimized. Methods: In a series of studies, we tested the safety of personal care products containing oatmeal (creams, cleansers, lotions) by assessing their irritant/allergenic potential on repeat insult patch testing, in safety-in-use and ocular studies using subjects with nonsensitive and sensitive skin. We also tested the skin moisturizing and repair properties of an oatmeal-containing skin care product for dry skin. Results: We found that oatmeal-containing personal care products had very low irritant potential as well as a very low allergenic sensitization potential. Low-level reactions were documented in 1.0% of subjects during the induction phase of repeat insult patch testing; one of 2291 subjects developed a persistent but doubtful low-level reaction involving edema during the challenge phase in repeat insult patch testing. No allergies were reported by 80 subjects after patch testing after in-use application. Sustained skin moisturizing was documented in subjects with dry skin that lasted up to 2 weeks after product discontinuation. Conclusion: Our results demonstrate that colloidal oatmeal is a safe and effective ingredient in personal care products. No allergies were reported by consumers of 445,820 products sold during a 3-year period.
ACCESSION #
84690827

 

Related Articles

  • Choosing Healthier Dietary Fats. ETINGIN, ORLI R. // Women's Health Advisor;Aug2019, Vol. 23 Issue 8, p1 

    No abstract available.

  • O’LENICK RETIRES FROM SILTECH.  // Happi: Household & Personal Products Industry;Feb2020, Vol. 57 Issue 2, p168 

    No abstract available.

  • Pondering Pruritus. Kuznar, Wayne // Dermatology Times;Jun2003, Vol. 24 Issue 6, p46 

    Discusses the importance of understanding the pathophysiologic processes of pruritis associated with atopic dermatitis in developing effective treatment approaches. Reasons why nerve fibers are important in atopic dermatitis; Involvement of histamine in atopic dermatitis; Treatment approaches...

  • Serum Autotaxin Levels Correlate with Pruritus in Patients with Atopic Dermatitis. Nakao, Momoko; Sugaya, Makoto; Suga, Hiraku; Kawaguchi, Makiko; Morimura, Sohshi; Kai, Hiromichi; Ohmatsu, Hanako; Fujita, Hideki; Asano, Yoshihide; Tada, Yayoi; Kadono, Takafumi; Sato, Shinichi // Journal of Investigative Dermatology;Jun2014, Vol. 134 Issue 6, p1745 

    A letter to the editor is presented regarding the correlation of the levels of serum autotaxin (ATX) with the pruritus of cholestasis in patients with atopic dermatitis (AD).

  • Activation Markers in Severe Atopic Dermatitis Following Extracorporeal Photochemotherapy. Radenhausen, Michael // Acta Dermato-Venereologica;Jan2003, Vol. 83 Issue 1, p49 

    Atopic dermatitis (AD) is a troublesome inflammatory skin disease characterized by severe pruritus, typical eczematous morphology and a chronic relapsing course often associated with increased IgE levels. The pathogenesis of AD remains unknown. Lesional skin in AD is characterized by a dermal...

  • Biocides in Personal Care - 2011 Edition - The Global Consumption of Biocides in Personal Care Was $820 Mln at Active Manufacture Level In 2011.  // Biomedical Market Newsletter;10/17/2011, Vol. 21, p164 

    The article focuses on the report "Biocides in Personal Care - 2011 Edition," by Research & Markets Ltd. (R&M) which highlights the global consumption and market performance of biocide products in personal care in 2011. The report provides analysis on industry trends, assessment on the impact of...

  • Dermatology Clinic. Red, itchy scaling plaques on a toddler. ROBBINS, KERRI // Clinical Advisor;Jul2011, Vol. 14 Issue 7, p87 

    The article presents a case study of a two-year-old girl with scaling plaques diagnosed as atopic dermatitis (AD). It states that the patient had tacrolimus therapy to her faces and triamcinolone therapy to affected areas on her body. It says that treatment of AD requires antipruritic and...

  • Atopic Dermatitis: Molecular Mechanisms, Clinical Aspects and New Therapeutical Approaches. Galli, E.; Cicconi, R.; Rossi, P.; Casati, A.; Brunetti, E.; Mancino, G. // Current Molecular Medicine;Mar2003, Vol. 3 Issue 2, p127 

    Atopic dermatitis (AD) is a genetically determinated, chronic inflammatory skin disorder associated with cutaneous erythema and severe pruritus, affecting 10-15% of children with increasing incidence and socio-economical relevance. Frequently, AD is associated with development of allergic...

  • Managing the itch of atopic dermatitis in children. Sabbagh, Leslie // Dermatology Times;Mar1995, Vol. 16 Issue 3, p44 

    Discusses the control of itching in atopic dermatitis among infants and children. Flare factors; Reassurance of parents; Steroids as mainstay treatments; Crusting.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics