Choroid plexus coagulation for hydrocephalus not due to CSF overproduction: a review

Zhu, Xianlun; Rocco, Concezio
January 2013
Child's Nervous System;Jan2013, Vol. 29 Issue 1, p35
Academic Journal
Objective: This study aims to review the role of choroid plexus coagulation (CPC) for hydrocephalus not due to CSF overproduction. Methods: The literatures covering CPC/cauterization/extirpation and ablation searched through PubMed were reviewed. Results: The history of CPC goes back to early 1900s by open surgery. It has evolved to mainly an endoscopic surgery since 1930s. With the development of other treatment methods and the understanding of CSF dynamics, the application of CPC dramatically decreased by 1970s. In late 2000, there was a resurgence of CPC in combination with endoscopic third ventriculostomy (ETV) performed in Africa. Conclusions: CPC remains one of the options for the treatment of hydrocephalus in selected cases. CPC might provide a temporary reduction in CSF production to allow the further development of CSF absorption in infant. Adding CPC to ETV for infants with communicating hydrocephalus may increase the shunt independent rate thus avoiding the consequence of late complication related to the shunt device. This is important for patients who are difficult to be followed up, due to geographical and/or socioeconomic constrains. Adding CPC to ETV for obstructive hydrocephalus in infant may also increase the successful rate. Furthermore, CPC may be an option for cases with high chance of shunt complication such as hydranencephaly. In addition, CPC may act as an adjunct therapeutic measure for complex cases such as multiloculated hydrocephalus. In comparison with the traditional treatment of CSF shunting, the role of CPC needs to be further evaluated in particular concerning the neurocognitive development.


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