Study of Opportunistic Infections In HIV Seropositive Patients Admitted to Community Care centre (CCC), KIMS Narketpally

Takalkar, Anant A.; Saiprasad, G. S.; Prasad, V. G.; Madhekar, Narendra S.
January 2012
Biomedical Research (0970-938X);Jan-Mar2012, Vol. 23 Issue 1, p139
Academic Journal
The human immunodeficiency virus (HIV) infection leading to Acquired Immunodeficiency Syndrome (AIDS) causes progressive decline in immunological response in people living with HIV/AIDS (PLWHA) making them susceptible to a variety of and opportunistic infections which are responsible for morbidity and mortality. Community Care Centres (CCC) have been started as a measure to ensure compliance of antiretroviral treatment. Detailed history taking, clinical examination and laboratory tests were carried out in 110 patients. The pattern of opportunistic infections in people living with HIV/AIDS (PLWHA) attending CC was studied. The presenting symptoms were fever (82.2%), weight loss (65.8%), cough & dyspnoea (45.5%) and diarrhoea (41.7%). One or more opportunistic infections were observed in 63 patients (57%). Commonly observed were pulmonary tuberculosis (52.3%), candidiasis (39%), cryptosporidial diarrhoea (30.1%) and Pneumocystis Carinii Pneumonia (PCP) (14.2%). In 46.4% of cases CD4 count was less than 200. Findings point to the importance of early diagnosis and treatment of opportunistic infections in order to improve quality and expectancy of life.


Related Articles

  • Mortality among pulmonary tuberculosis and HIV-1 co-infected Nigerian children being treated for pulmonary tuberculosis and on antiretroviral therapy: a retrospective cohort study. Ebonyi, Augustine O.; Oguche, Stephen; Agbaji, Oche O.; Sagay, Atiene S.; Okonkwo, Prosper I.; Idoko, John A.; Kanki, Phyllis J. // Germs;Dec2016, Vol. 6 Issue 4, p139 

    Background Mortality data, including the risk factors for mortality in HIV-infected children with pulmonary TB (PTB) being treated for PTB and who are on antiretroviral therapy (ART), are scarce in Nigeria. We determined the mortality rate and risk factors for mortality among such children, at...

  • Timing, rates, and causes of death in a large South African tuberculosis programme. Field, Nigel; Lim, Megan S. C.; Murray, Jill; Dowdeswell, Robert J.; Glynn, Judith R.; Sonnenberg, Pam // BMC Infectious Diseases;2014, Vol. 14 Issue 1, p1 

    Background: Tuberculosis (TB) mortality remains high across sub-Saharan Africa despite integration of TB and HIV/ART programmes. To inform programme design and service delivery, we estimated mortality by time from starting TB treatment. Methods: Routinely collected data on TB treatment, vital...

  • Mortality Among Patients with Tuberculosis and Associations with HIV Status -- United States, 1993-2008. Shah, S.; Cain, K.; Marks, S.; Cavanaugh, J. // MMWR: Morbidity & Mortality Weekly Report;11/26/2010, Vol. 59 Issue 46, p1509 

    The article discusses a study on the impact of the HIV on the risk of death on patients with tuberculosis (TB) during treatment in the U.S. from 1993 to 2008. Studies showed that HIV patients are more at risk of acquiring TB and in turn have a higher mortality risk where there is limited access...

  • Voucher Incentives Improve Linkage to and Retention in Care Among HIV-Infected Drug Users in Chennai, India. Solomon, Sunil Suhas; Srikrishnan, Aylur K.; Vasudevan, Canjeevaram K.; Anand, Santhanam; Kumar, Muniratnam Suresh; Balakrishnan, Pachamuthu; Mehta, Shruti H.; Solomon, Suniti; Lucas, Gregory M. // Clinical Infectious Diseases;Aug2014, Vol. 59 Issue 4, p589 

    Modest voucher incentives were associated with significantly better linkage to and retention in care but not with virologic suppression among human immunodeficiency virus (HIV)-infected drug users in Chennai, India, a population with high HIV disease burden and low access to antiretroviral...

  • Causes of Death among AIDS Patients after Introduction of Free Combination Antiretroviral Therapy (cART) in Three Chinese Provinces, 2010–2011. Wang, Liyan; Ge, Lin; Wang, Lu; Morano, Jamie P.; Guo, Wei; Khoshnood, Kaveh; Qin, Qianqian; Ding, Zhengwei; Sun, Dingyong; Liu, Xiaoyan; Luo, Hongbing; Tillman, Jonas; Cui, Yan // PLoS ONE;10/27/2015, Vol. 10 Issue 10, p1 

    Introduction: Although AIDS-related deaths have had significant economic and social impact following an increased disease burden internationally, few studies have evaluated the cause of AIDS-related deaths among patients with AIDS on combination anti-retroviral therapy (cART) in China. This...

  • Cancer Incidence following Expansion of HIV Treatment in Botswana. Dryden-Peterson, Scott; Medhin, Heluf; Kebabonye-Pusoentsi, Malebogo; IIISeage, George R.; Suneja, Gita; Kayembe, Mukendi K. A.; Mmalane, Mompati; Rebbeck, Timothy; Rider, Jennifer R.; Essex, Myron; Lockman, Shahin // PLoS ONE;8/12/2015, Vol. 10 Issue 8, p1 

    Background: The expansion of combination antiretroviral treatment (ART) in southern Africa has dramatically reduced mortality due to AIDS-related infections, but the impact of ART on cancer incidence in the region is unknown. We sought to describe trends in cancer incidence in Botswana during...

  • Cohort Profile: Antiretroviral Therapy Cohort Collaboration (ART-CC). May, Margaret T; Ingle, Suzanne M; Costagliola, Dominique; Justice, Amy C; de Wolf, Frank; Cavassini, Matthias; D’Arminio Monforte, Antonella; Casabona, Jordi; Hogg, Robert S; Mocroft, Amanda; Lampe, Fiona C; Dabis, François; Fätkenheuer, Gerd; Sterling, Timothy R; del Amo, Julia; Gill, M John; Crane, Heidi M; Saag, Michael S; Guest, Jodie; Brodt, Hans-Reinhard // International Journal of Epidemiology;Jun2014, Vol. 43 Issue 3, p691 

    The advent of effective combination antiretroviral therapy (ART) in 1996 resulted in fewer patients experiencing clinical events, so that some prognostic analyses of individual cohort studies of human immunodeficiency virus-infected individuals had low statistical power. Because of this, the...

  • Scaling up antiretroviral therapy for HIV-infected children in Côte d'Ivoire: determinants of survival and loss to programme. Anaky, M.-F.; Duvignac, J.; Wemin, L.; Kouakoussui, A.; Karcher, S.; Touré, S.; Seyler, C.; Fassinou, P.; Dabis, F.; N'Dri-Yoman, T.; Anglaret, X.; Leroy, V. // Bulletin of the World Health Organization;Jul2010, Vol. 88 Issue 7, p490 

    Objective To investigate deaths and losses to follow-up in a programme designed to scale up antiretroviral therapy (ART) for HIV- infected children in Côte d'Ivoire. Methods Between 2004 and 2007, HIV-exposed children at 19 centres were offered free HIV serum tests (polymerase chain reaction...

  • HIV Testing and Treatment Among Tuberculosis Patients -- Kenya, 2006-2009. Sitienei, J.; Kipruto, H.; Nganga, L.; Ackers, M.; Odhiambo, J.; Laserson, K.; Nakashima, A. K.; Modi, S. // MMWR: Morbidity & Mortality Weekly Report;11/26/2010, Vol. 59 Issue 46, p1514 

    The article discusses a report on HIV data from Kenya's tuberculosis (TB) surveillance system from 2006 to 2009. The Kenya Division of Leprosy, Tuberculosis and Lung Disease (DLTLD) added HIV testing and treatment to its TB surveillance program at the recommendation of the World Health...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics