Can genes be blamed for obesity?
- Newest fat gene. // Joe Weider's Muscle & Fitness;Feb96, Vol. 57 Issue 2, p33
Reports on the discovery of a fat gene by researchers at the Johns Hopkins Medical Centers. Involvement of the beta-3 adrenergic receptor; Possible member of a group of factors producing the genetic component of obesity.
- Genes and obesity: Is there reason to change our behaviors? Weinsier, Roland L. // Annals of Internal Medicine;06/01/99, Vol. 130 Issue 11, p938
Editorial. Comments on the contribution of genes to the development of obesity. Various pathways in which genes can affect appetite and regulate food intake; propensity to be physically inactive partly determined by genotype; Contribution of genes to low energy body requirements; Environmental...
- Sex-specific genetic architecture of human fatness in Chinese: the SAPPHIRe Study. Chiu, Y.-F.; Chuang, L.-M.; Kao, H.-Y.; Shih, K.-C.; Lin, M.-W.; Lee, W.-J.; Quertermous, T.; Curb, J.; Chen, I.; Rodriguez, B.; Hsiung, C. // Human Genetics;Nov2010, Vol. 128 Issue 5, p501
To dissect the genetic architecture of sexual dimorphism in obesity-related traits, we evaluated the sex-genotype interaction, sex-specific heritability and genome-wide linkages for seven measurements related to obesity. A total of 1,365 non-diabetic Chinese subjects from the family study of the...
- Identification of the gene that, when mutated, causes the human obesity syndrome BBS4. Mykytyn, Kirk; Braun, Terry; Carmi, Rivka; Haider, Neena B.; Searby, Charles C.; Shastri, Mythreyi; Beck, Gretel; Wright, Alan F.; Iannaccone, Alessandro; Elbedour, Khalil; Riise, Ruth; Baldi, Alfonso; Raas-Rothschild, Annick; Gorman, Susan W.; Duhl, David M.; Jacobson, Samuel G.; Casavant, Thomas; Stone, Edwin M.; Sheffield, Val C. // Nature Genetics;Jun2001, Vol. 28 Issue 2, p188
Bardet?Biedl syndrome (BBS, MIM 209900) is a heterogeneous autosomal recessive disorder characterized by obesity, pigmentary retinopathy, polydactyly, renal malformations, mental retardation, and hypogenitalism. The disorder is also associated with diabetes mellitus, hypertension, and congenital...
- Mapping obesity genes. // Healthy Weight Journal;Jan/Feb2001, Vol. 15 Issue 1, p3
Editorial. Presents an update on the efforts of researchers at Laval University in Quebec City, Quebec to identify human obesity genes and markers. Overview of findings; Discussion on the attempts to relate DNA sequence variation in specific genes to obesity phenotypes.
- GET THAT GENE IN THERAPY! // Joe Weider's Muscle & Fitness;Jun2001, Vol. 62 Issue 6, p56
Provides information on Beacon, an obesity gene. How the gene was discovery; Importance in weight loss.
- LOWER LEPTIN LEVELS. // Science Teacher;May2000, Vol. 67 Issue 5, p12
Reports on a study showing that physically active people have low levels of leptin, the so-called fat hormone. Production of leptin by the body's fat cells; Role in causing obesity; Characteristics of men whose leptin levels were the highest; Possible role in the development of diabetes.
- Obesity related phenotypes in families selected for extreme obesity and leanness. Price, R A; Reed, D R; Lee, J H // International Journal of Obesity & Related Metabolic Disorders;May1998, Vol. 22 Issue 5, p406
BACKGROUND: Obesity is a multigenic trait, and special methods and sampling designs are needed for gene identification. OBJECTIVE: To describe characteristics of families selected to increase information for genetic linkage studies of obesity. DESIGN: Families having extremely obese siblings...
- Chronic high-fat diet in fathers programs ?-cell dysfunction in female rat offspring. Sheau-Fang Ng; Lin, Ruby C. Y.; Laybutt, D. Ross; Barres, Romain; Owens, Julie A.; Morris, Margaret J. // Nature;10/21/2010, Vol. 467 Issue 7318, p963
The global prevalence of obesity is increasing across most ages in both sexes. This is contributing to the early emergence of type 2 diabetes and its related epidemic. Having either parent obese is an independent risk factor for childhood obesity. Although the detrimental impacts of diet-induced...