Home versus outpatient ultraviolet B phototherapy for mild to severe psoriasis: pragmatic multicentre randomised controlled non-inferiority trial (PLUTO study)

Koek, Mayke B. G.; Buskens, Erik; van Weelden, Huib; Steegmans, Paul H. A.; Bruijnzeel-Koomen, Carla A. F. M.; Sigurdsson, Vigfús
May 2009
BMJ: British Medical Journal (Overseas & Retired Doctors Edition;5/16/2009, Vol. 338 Issue 7704, p1181
Academic Journal
The article focuses on a research conducted to determine whether home-based ultraviolet B phototherapy is equally safe and effective as ultraviolet B phototherapy in an outpatient setting for psoriasis patients. The study was conducted on 196 patients with psoriasis at the dermatology departments of 14 hospitals in the Netherlands. The effectiveness of the therapies was measured by the proportion of patients with a 50 percent or more reduction of the baseline psoriasis area and severity index or self administered psoriasis area and severity index. The study found that both the therapies were equally safe and effective in the treatment of psoriasis and that ultraviolet B phototherapy at home resulted in a lower burden of treatment and a greater satisfaction amongst patients.


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