TITLE

Determination of access blood flow from ionic dialysance: Theory and validation

AUTHOR(S)
Mercadal, Lucile; Hamani, Aziz; Béné, Bernard; Petitclerc, Thierry
PUB. DATE
October 1999
SOURCE
Kidney International;Oct1999, Vol. 56 Issue 4, p1560
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Determination of access blood flow from ionic dialysance: Theory and validation. Background. Several noninvasive techniques have been recently developed for calculating blood flow rate of vascular access in hemodialyzed patients from the on-line measurement of recirculation ratio by injecting a saline bolus when the blood lines are reversed. Here we describe a new noninvasive method based on ionic dialysance measurements without the need of a saline bolus. Methods. Mathematical modeling allows to calculate blood flow in vascular access (QA ) from the recirculation ratio (Rrev ) measured when the blood lines are reversed, without the need to stop ultrafiltration, by using the formula: QA = (QB -QF ) 1 -Rrev /Rrev where QB is the blood flow at the dialyzer inlet and QF the ultrafiltration rate. Because the ionic dialysance takes recirculation into account, we tested a new method to assess QA from the measurement of ionic dialysance at normal (D) and reverse (Drev ) positions of the blood lines for the same QB . Assuming the absence of access recirculation at normal position of the blood lines, mathematical modeling provides the following relationship: QA = (D - QF )Drev /D - Drev . The estimation of QA from measurement of ionic dialysance (QA-ID ) was compared in 28 patients to the estimation of QA by ultrasound dilution technique (QA-US ). Results. The two methods were strongly correlated (QA-ID = 1.24 * QA-US , r 2 = 0.86, P < 0.0001). The difference between QA-ID and QA-US was 107 ± 387 ml/min (mean ±sd). Conclusions. Our method provides a valuable estimation of the vascular access flow and is fully noninvasive, easy to perform (no need of bolus injection and of accurate...
ACCESSION #
5865305

 

Related Articles

  • New system for single-needle dialysis. Cunningham, John; Sharman, V.L.; Hawkes, A.P.; Goodwin, F.J.; Marsh, F.P. // British Medical Journal;10/25/1980, Vol. 281 Issue 6248, p1109 

    Examines the efficacy latest system for single-needed dialysis. Maintenance of high blood flow rates; Prevention of excessive pressure fluctuation; Safe application of positive dialysate pressure to control ultrafiltration.

  • Vascular access surveillance: an ongoing controversy. Paulson, William D; Moist, Louise; Lok, Charmaine E // Kidney International;Jan2012, Vol. 81 Issue 2, p132 

    Hemodialysis vascular access surveillance continues to be widely recommended despite ongoing controversy as to its benefit in prolonging access patency compared with clinical monitoring alone. The most common screening tests are access blood flow and dialysis venous pressure measurements. When...

  • Theory and validation of access flow measurement by dilution technique during hemodialysis. Krivitski, Nikolai M. // Kidney International;Jul1995, Vol. 48 Issue 1, p244 

    The theory shows that access flow can be measured by the dilution technique by reversal of the blood dialysis lines with the venous outlet facing the access stream; (1.) with one dilution sensor in arterial line and two injections Equation (6); (2.) with two matched dilution sensors on the...

  • Pharmacokinetic Studies in Hemodialysis Patients. Atkinson, A. J.; Umans, J. G. // Clinical Pharmacology & Therapeutics;Nov2009, Vol. 86 Issue 5, p548 

    The article focuses on the importance of well-designed pharmacokinetic studies with useful hemodialysis data in patients undergoing hemodialysis. It mentions that artificial kidney provides opportunity in blood flow measurement in pharmacokinetic perspective. It imparts that proper estimation of...

  • Rotating permanent magnet excitation for blood flow measurement. Nair, Sarath; Vinodkumar, V.; Sreedevi, V.; Nagesh, D.; Nair, Sarath S; Nagesh, D S // Medical & Biological Engineering & Computing;Nov2015, Vol. 53 Issue 11, p1187 

    A compact, portable and improved blood flow measurement system for an extracorporeal circuit having a rotating permanent magnetic excitation scheme is described in this paper. The system consists of a set of permanent magnets rotating near blood or any conductive fluid to create high-intensity...

  • CONSIDERATIONS ABOUT ELECTRICAL SAFETY IN THE DIALYSIS PROCESS. Ianosi, E. // Annals of DAAAM & Proceedings;2010, p915 

    The dialysis process is an extra corporal epuration method of the patients blood by the toxins resulted in the metabolic process of the human body. It is applied when the kidneys can't achieve their normal functions, by using a dialysis apparatus and a dialyzer. During hemodialysis, the dialysis...

  • Resistance Within Hemodialysis Shunts Predicts Patency. Bui, Trung D.; Gordon, Ian L.; Parashar, Amish; Vo, David; Wilson, Samuel E. // Vascular & Endovascular Surgery;Aug/Sep2006, Vol. 40 Issue 4, p295 

    The authors examined the relationship between patency after thrombectomy of clotted dialysis grafts and intraoperative measurements of flow (Q), pressure gradient (PGR), and longitudinal resistance (RL). Eighteen thrombosed arteriovenous (AV) grafts underwent 21 thrombectomies. Pressures at...

  • Compliance and reactivity of the peripheral venous system in chronic intermittent hemodialysis. Kooman, Jeroen P.; Wijnen, Jef A. G.; Draaijer, Petra; Van Bortel, Luc M. A. B.; Gladziwa, Ulrich; Peltenburg, Henricus G.; Struyker-Boulder, Harry A. J.; Van Hooff, Johannes P.; Leunissen, Karel M. L. // Kidney International;Apr1992, Vol. 41 Issue 4, p1041 

    A reduced venous compliance and/or inadequate venoconstriction could impair hemodynamics during hemodialysis. Therefore, compliance and reactivity of the peripheral venous system were assessed in hemodialysis patients and controls using strain gauge plethysmography. Reactivity of the venous...

  • The Details of Dialysis. Noblitt, John // 24x7;Dec2015, Vol. 20 Issue 12, p14 

    The article focuses on dialysis, a medical process that filters waste salts and fluids from the blood with two forms such as peritoneal dialysis and hemodialysis. Topics discussed include the two categories of peritoneal dialysis such as continuous ambulatory peritoneal dialysis (CAPD) and...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics