TITLE

Randomized Controlled Trials

AUTHOR(S)
Torpy, Janet M.
PUB. DATE
March 2010
SOURCE
JAMA: Journal of the American Medical Association;3/24/2010, Vol. 303 Issue 12, p1216
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article offers information on randomized controlled trials. Randomized controlled trial is a type of clinical trial where study participants are randomly assigned to receive treatment, in an effort to determine outcomes based on the treatment and not by other factors. Clinical trials are usually designed to examine the safety and efficacy of a treatment. Volunteers in clinical trials sign an informed consent, which explains the benefits of such trial. Other issues that should be considered when participating in a clinical trial are also cited.
ACCESSION #
48732010

 

Related Articles

  • Randomized Controlled Trials. Torpy, Janet M.; Glass, Richard M.; Lynm, Cassio // JAMA: Journal of the American Medical Association;6/21/2006, Vol. 295 Issue 23, p2812 

    The JAMA Patient Page provides information on randomized controlled trials in medical research. Clinical trials are usually designed to consider efficacy and safety of a treatment and should include an informed consent process. Other ideas explained include placebo treatment, single-blind and...

  • Ethics and Regulatory Complexities for Pragmatic Clinical Trials. Sugarman, Jeremy; Califf, Robert M. // JAMA: Journal of the American Medical Association;6/18/2014, Vol. 311 Issue 23, p2381 

    The article discusses the use of pragmatic clinical trials (PCT) to overcome challenges in medical research. Topics discussed include PCTs involving patients in routine clinical practice settings and comparative effectiveness research (CER), the benefits of research methods that use cluster...

  • The Ethics of Research in Emergency Medicine. Biros, Michelle H. // Science & Engineering Ethics;Sep2007, Vol. 13 Issue 3, p279 

    The article comments on ethical issues that arise in emergency research. Researchers face difficulties in dealing with human subjects when doing research in emergency settings. Aside from the challenges encountered in designing and implementing studies that include critically ill patients, it is...

  • Start-up consultations improve site compliance.  // Medical Ethics Advisor;Feb2011, Vol. 27 Issue 2, p22 

    The article reports on start-up consultation, a study created to improve clinical trial site compliance in the U.S. It mentions that this type of consultation involves human subject research (HSR) regulatory experts who works with researchers to ensure that their documentation and consent...

  • Aging strategies call for 'reformed consent'  // IRB Advisor;Dec2009, Vol. 9 Issue 12, p142 

    The article calls for the reform of written informed consent (IC) forms used in clinical trial research involving human subjects. It suggests the presentation of IC document in a slide show accompanied by a narrative. Also recommended is the presentation of IC information in a way that would...

  • Issues concerning informed consent.  // Medical Ethics Advisor;Jul2011, Vol. 27 Issue 7, p78 

    The article focuses on the issues concerning informed consent in first-in human clinical trials. It notes that due to the uncertainties associated with first-in human studies, informed consent provide participants with the information needed in making decisions. It also states that medical...

  • Taking stock of financial disclosures: Most want to know, won't drop out.  // IRB Advisor;Dec2008, Vol. 8 Issue 12, p133 

    The article discusses the findings of a study that surveyed 470 people about their reaction to informed consent documents that detailed such interests. The study revealed that knowing that an investigator has a financial interest in a clinical trial does not substantially affect people's...

  • Costs to Subjects for Research Participation and the Informed Consent Process: Regulatory and Ethical Considerations. Iltis, Ana S. // IRB: Ethics & Human Research;Nov/Dec2004, Vol. 26 Issue 6, p9 

    Examines the ethical aspects of charging prospective clinical trial subjects particularly on expected costs, e.g., tests or services that will likely not be covered by third party payers. Charging research subjects for health system related costs; Ethical obligation to disclose health system...

  • MedEconomics: In a nutshell - The ethics of clinical trials.  // GP: General Practitioner;5/23/2012, p31 

    The article discusses the ethical issues related to clinical trials. All trials, interventions or evaluations must be approved by a research ethical committee (REC) to ensure they are fair to patients and ethical. RECs have the power to stop a project if they have any concerns about patient...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics