Feasibility of a PVDF Receiver for Monitoring of Transcranial Therapy

O'Reilly, Meaghan A.; Hynynen, Kullervo
March 2010
AIP Conference Proceedings;3/9/2010, Vol. 1215 Issue 1, p212
Conference Proceeding
An MRI compatible PVDF receiver was designed and manufactured for integration into a transcranial therapy array. 4.8 mm diameter, 110 μm thick PVDF film was air-backed by clamping it across brass tubing. A preamplifier was enclosed within the tubing to improve SNR and drive the long coaxial cables required to reach outside the MRI. The receiver was mounted inside a ring element from an existing array. The receiver performance was compared with a commercial needle hydrophone and tested for MRI compatibility. The PVDF receiver displayed a higher sensitivity than the needle hydrophone and a better capability to reject electrical coupling with the transmit element. MRI image artifacts created by the device were small, and diagnostic ultrasound was possible with the device while simultaneously obtaining an MRI image. Microbubble contrast agent was sonicated both directly, and through a fragment of human skull. The transmit/receive pair was successful in sonicating the microbubbles transcranially and detecting the returning microbubble emissions. A second generation receiver with a diameter of 2.4 mm was manufactured, without sacrificing sensitivity, to increase the field of view of the device. Future work will focus on developing a multi-element receiver array and its testing for brain treatment monitoring.


Related Articles

  • Magnetic microbubble-mediated ultrasound-MRI registration based on robust optical flow model. Mo Hou; Chunxiao Chen; Dalin Tang; Shouhua Luo; Fang Yang; Ning Gu // BioMedical Engineering OnLine;Aug2015 Supplement, Vol. 14 Issue 1, p1 

    Background: As a dual-modality contrast agent, magnetic microbubbles (MMBs) can not only improve contrast of ultrasound (US) image, but can also serve as a contrast agent of magnetic resonance image (MRI). With the help of MMBs, a new registration method between US image and MRI is presented....

  • INTRAVASCULAR MR AND SAFETY. Ladd, M.E.; Quick, H.H. // Acta Radiologica;Apr2000 Supplement 422, Vol. 41, p68 

    Proposes a method for reducing or eliminating unbalanced currents on the shield of coaxial cables connecting the antenna to the scanner of magnetic resonance imaging systems which lead to radio frequency heating. Construction of triaxial cable with a practical diameter; Changes in the boundary...

  • Noninvasive imaging of carotid artery disease: critically appraised topic. Jenkins, Richard H.; Mahal, Ravinder; MacEneaney, Peter M. // Canadian Association of Radiologists Journal;Apr2003, Vol. 54 Issue 2, p121 

    Discusses modalities for the non-invasive imaging of carotid artery disease. Duplex Doppler ultrasonography; Magnetic resonance angiography; Computed tomography angiography.

  • Image Fusion of Diagnostic Ultrasound with Other Modalities. Ewertsen, Caroline; Nielsen, Kristina R.; Hesse, Birger; Nielsen, Michael B. // Current Medical Imaging Reviews;2009, Vol. 5 Issue 3, p150 

    Image fusion between different "anatomic" imaging modalities such as CT or MRI with the "functional" radionuclide images (positron emission tomography, PET, or single photon emission tomography, SPECT) has been shown to give very useful clinical information. This image fusion technique is now...

  • Ultrasonic Diagnosis of Fetal Bone and Small Parts. Sekiya, Takao; Murotsuki, Jun; Nishizawa, Haruki; Udagawa, Yasuhiro // Donald School Journal of Ultrasound in Obstetrics & Gynecology;Jan-Mar2011, Vol. 5 Issue 1, p45 

    The prenatal diagnosis of fetal bone and small parts is a challenging task to the variable disorders and large number of possible diagnosis. Fetal limb anomalies may be congenital or acquired in utero. The former occur as anomalies either systemically or, in some limbs, due to hereditary or...

  • Ultrasonic diagnosis of biliary atresia: A retrospective analysis of 20 patients. Shi-Xing Li; Yao Zhang; Mei Sun; Bo Shi; Zhong-Yi Xu; Ying Huang; Zhi-Qin Mao; Rodriguez, Damian Casadeus // World Journal of Gastroenterology;6/14/2008, Vol. 14 Issue 22, p3579 

    AIM: To investigate the clinical value of ultrasono-graphic diagnosis of biliary atresia (BA), a retrospective analysis of the sonogram of 20 children with BA was undertaken. METHODS: Ultrasonography (US) was performed in 20 neonates and infants with BA, which was confirmed with cholangiography...

  • DIAGNOSIS OF AN ULNAR COLLATERAL LIGAMENT TEAR USING MUSCULOSKELETAL ULTRASOUND IN A COLLEGIATE BASEBALL PITCHER: A CASE REPORT. Wood, Nate; Konin, Jeff G.; Nofsinger, Charles // North American Journal of Sports Physical Therapy;Dec2010, Vol. 5 Issue 4, p227 

    Objective: To demonstrate a comparative diagnostic approach between magnetic resonance imaging (MRI) and musculoskeletal ultrasound for detecting UCL trauma of the elbow in a collegiate baseball pitcher. Background: A 19 year-old male baseball pitcher with no previous history of an elbow injury...

  • Accuracy of computer-aided ultrasound as compared with magnetic resonance imaging in the evaluation of nonalcoholic fatty liver disease in obese and eutrophic adolescents. Ribas do Nascimento, José Hermes; Bernardi Soder, Ricardo; Epifanio, Matias; Baldisserotto, Matteo // Radiologia Brasileira;jul/ago2015, Vol. 48 Issue 4, p225 

    Objective: To compare the accuracy of computer-aided ultrasound (US) and magnetic resonance imaging (MRI) by means of hepatorenal gradient analysis in the evaluation of nonalcoholic fatty liver disease (NAFLD) in adolescents. Materials and Methods: This prospective, cross-sectional study...

  • Prolapsing left atrial myxoma: preoperative diagnosis using a multimodal imaging approach with magnetic resonance imaging and real-time three-dimensional echocardiography. Butz, T.; Scholtz, W.; Körfer, J.; Maleszka, A.; Jategaonkar, S.; Meissner, A.; Trappe, H.J.; Körfer, R.; Horstkotte, D.; Kleikamp, G.; Faber, L. // European Journal of Echocardiography;May2008, Vol. 9 Issue 3, p430 

    Real-time three-dimensional echocardiography (RT3DE) is a new promising technique for the evaluation of intracardiac masses. We present the diagnostic work-up using a multimodal-imaging approach in a 74-year-old patient with a prolapsing tumour in the left atrium suggestive of a myxoma, causing...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics