Multidisipliner yeni bir bilim dalı: biyoinformatik ve tıpta uygulamaları

Polat, Mümin; Karahan, Aynur Gül
September 2009
Medical Journal of Suleyman Demirel University;Sep2009, Vol. 16 Issue 3, p41
Academic Journal
A healthy evaluation of the information gathered on biological systems and incidents is possible due to bioinformatics, a new and interdisciplinary scientific branch growing out of the integration of medicine, biochemistry, chemistry, informatics, math and statistics as well as biology. Bioinformatics is based on making use of informatics technologies in order to solve biological problems and helps biological events to be explained at a molecular level. Bioinformatics is theation of databases in order to create and store biological information. Bioinformatics play an important role in medical sciences. Recent applications in medical sciences have focused on gene expression analyses. In general, expressions of cells that are affected from different diseases are compiled and compared to those of healthy cells and differences between them are used to diagnose the disease and design the target medicine. Through this, it could be possible to design the components that can be attached the protein subject to expression, and what is more, transcription regulators causing change in expression level can be determined. In this context, what the points at issue are that micro-array experiments are carried out, and response is assessed in pharmacological practices, thus obtaining pre-information on toxicity of the medicines to be tested. In this compilation, we have tried to explain the use of bioinformatics, a very recent scientific branch, in medicine and pharmacology.


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