Consolidation Period in Alveolar Distraction: A Pilot Histomorphometric Study in the Mandible of the Beagle Dog

Cano, Jorge; Campo, Julián; Gonzalo, Juan Carlos; Bascones, Antonio
May 2006
International Journal of Oral & Maxillofacial Implants;May/Jun2006, Vol. 21 Issue 3, p380
Academic Journal
Purpose: Osteogenic alveolar distraction remains in an experimental stage. The present study aimed to compare histologic and histomorphometric results with 2 different consolidation periods (4 and 8 weeks) to determine which period obtained better bone quality after distraction with a prototype alveolar distractor. Materials and Methods: Five beagle dogs were used. Four underwent alveolar distraction in an edentulous segment of the right mandible. After a 7-day latency period, distraction was carried out at a rate of 1 mm/d for 5 days; the consolidation period was 4 weeks in 2 dogs (group 1), and 8 weeks in the other 2 (group 2). The fifth dog was used as control (group 3); it underwent removal of its right premolars but not distraction. Histologic and histomorphometric studies were conducted. Results: One animal from each distraction group was withdrawn from the study because of wound dehiscence that allowed invasion of mucosa into the distraction chamber, which was incompatible with bone regeneration. In the group 1 animal, a predominance of immature woven bone was observed in the distraction chamber, whereas the group 2 animal showed a predominance of immature parallel-fibered bone. The group 1 and 2 animals that remained in the study differed in bone area density in the distraction chamber (36.61% ± 9.79% versus 58.72% ± 8.30%), bone perimeter in the distraction chamber (262.89 ± 10.46 mm versus 201.44 ± 22.64 mm), total height attained (21.31 ± 0.32 mm versus 18.37 ± 0.50 mm), lingual trabecular width (134.00 ± 15.56 versus 229.50 ± 29.24), buccal trabecular width (90.00 ± 4.24 mm versus 154.50 ± 21.64 mm), lingual osteoid area density (4.08% ± 0.46% versus 1.61% ± 0.33%), and buccal osteoid area density (3.75% ± 1.28% versus 2.09% ± 0.79%). Conclusion: Quantitative and qualitative differences in newly formed bone were observed after 4 and 8 weeks of consolidation. These preliminary results serve as a basis for further experimental research with larger samples and for clinical studies.


Related Articles

  • The Influence of Functional Use of Endosseous Dental Implants on the Tissue-implant Interface. II. Clinical Aspects. BRUNSKI, JOHN B.; MOCCIA, JR., AQUILANTE F.; POLLACK, SOLOMON R.; KOROSTOFF, EDWARD; TRACHTENBERG, DON I. // Journal of Dental Research;Oct1979, Vol. 58 Issue 10, p1970 

    Functional and non-functional endosseous dental implants were clinically compared in beagle mandibles for up to one year post-operatively. Differing biomechanical conditions led to clinical differences between functional and non-functional implants. Typical clinical tests, however, did not...

  • Stability of the Mucosal Topography Around Single-Tooth Implants and Adjacent Teeth: 1-Year Results. Grunder, Ueli // International Journal of Periodontics & Restorative Dentistry;Feb2000, Vol. 20 Issue 1, p10 

    This study evaluated the soft tissue stability around 10 single-tooth implants. All cases were treated following the same protocol, which included guided bone regeneration and connective tissue grafting. One year after prothesis insertion the soft tissue shrinkage on the buccal side of the...

  • GBR and Autogenous Cortical Bone Particulate by Bone Scraper for Alveolar Ridge Augmentation: A 2-Case Report. Trombelli, Leonardo; Farina, Roberto; Marzola, Andrea; Itro, Angelo; Calura, Giorgio // International Journal of Oral & Maxillofacial Implants;2008, Vol. 23 Issue 1, p111 

    Scientific literature describes autogenous bone as the gold standard among graft materials for alveolar reconstructive procedures. Alveolar ridge augmentation has been clinically achieved with different forms of autogenous bone, including autogenous cortical bone particulate (ACBP). However, few...

  • The effect of different surface processing of BLB implants on osseointegration. Zhu Zhen-kun; Shao Shan; Lan Jing; Xu Xin // China Journal of Oral & Maxillofacial Surgery;2009, Vol. 7 Issue 1, p59 

    PURPOSE: To evaluate the effect of different surface processing of BLB implants on osseointegration. METHODS: Six Beagle dogs,thirty-six implants with different surface processing were divided into 2 groups (A:18 BLB III implants with HA+SLA surface processing ;B:18 BLB I implant with HA surface...

  • Human Histology of Allogeneic Block Grafts for Alveolar Ridge Augmentation: Case Report. Morelli, Thiago; Neiva, Rodrigo; Hom-Lay Wang // International Journal of Periodontics & Restorative Dentistry;2009, Vol. 29 Issue 6, p648 

    Autogenous bone grafts obtained from the mandibular symphysis or ramus are the primary donor sites for harvesting bone in the oral cavity to correct ridge deficiencies. Although such bone grafts can be successful, several concerns remain, such as donor site morbidity, nerve paresthesia,...

  • Influence of Static Overload on the Bony Interface Around Implants in Dogs. Miyamoto, Yasunari; Koretake, Katsunori; Hirata, Makoto; Kubo, Takayasu; Akagawa, Yasumasa // International Journal of Prosthodontics;2008, Vol. 21 Issue 5, p437 

    Purpose: The aim of this study was to investigate bony changes around selectively overloaded implants in dogs. Materials and Methods: Twelve adult male beagles were used: 4 animals each for control, 4-week-load, and 12-week-load groups. Three implants were placed on the right side of each of the...

  • The Effect of Low-level Laser Treatment on Maxillary Arch Dimensions after Palatal Surgery on Beagle Dogs. IN DE BRAEKT, M. M. H.; VAN ALPHEN, F. A. M.; KUIJPERS-JAGTMAN, A. M.; MALTHA, J. C. // Journal of Dental Research;Nov1991, Vol. 70 Issue 11, p1467 

    The effect of low-level laser treatment on maxillary arch dimensions after palatal surgery was investigated in Beagle dogs at an age of 12 weeks. A total of 30 dogs was used, and they were assigned to either a control group (Group C, n = 6) or one of two experimental groups (Group L, n = 12; and...

  • Rehabilitation of recurrent unicystic ameloblastoma using distraction osteogenesis and dental implants. Natashekara, M.; Chowdhary, Ramesh; Chandraker, Neeraj Kumar // Journal of Dental Implants;Jan2013, Vol. 3 Issue 1, p76 

    The ameloblastoma is a true neoplasm of odontogenic epithelial origin. Surgical resection of the ameloblastoma is well documented and accepted treatment modality. Vertical distraction of alveolar process is an efficient method for augmentation. This method of providing additional bone and soft...

  • Alternative Bone Expansion Technique for Implant Placement in Atrophic Edentulous Maxilla and Mandible. Demetriades, Neophytos; Park, Jong il; Laskarides, Constantinos // Journal of Oral Implantology;2011, Vol. 37 Issue 4, p463 

    This clinical review is an evaluation of the effectiveness of the split ridge bone augmentation technique performed in the atrophic maxilla and mandible with buccolingual bony defects. The osseointegration success of implant placement in the area of split ridge bone augmentation is assessed and...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics