TITLE

Remission of metabolic syndrome following a 15-week low-calorie lifestyle change program for weight loss

AUTHOR(S)
Lundgren, J. D.; Malcolm, R.; Binks, M.; O'Neil, P. M.
PUB. DATE
January 2009
SOURCE
International Journal of Obesity;Jan2009, Vol. 33 Issue 1, p144
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objective:To evaluate the rate of remission of metabolic syndrome (Met Syn) among patients undergoing a brief, low-calorie lifestyle change weight loss intervention and to compare the baseline characteristics of patients who were remitted and not remitted from Met Syn at post-treatment.Research Methods and Procedures:Obese adults (N=36) meeting criteria for Met Syn enrolled in an outpatient fee-for-service behavioral weight loss intervention. Participants were assessed on key Met Syn variables (waist circumference, blood pressure, triglycerides, high-density lipoprotein (HDL) cholesterol and fasting blood glucose) at pre- and post-treatment.Results:The majority of patients (61%) responded to treatment after a 9.9% mean weight loss. Although Met Syn responders did not differ significantly from Met Syn non-responders on any baseline Met Syn criterion variable, responders had significantly lower baseline body mass indices (BMI; kg/m2) and met criteria for fewer baseline Met Syn variables. As expected, Met Syn responders, compared with Met Syn non-responders, had significantly lower post-treatment waist circumference, systolic and diastolic blood pressures, triglycerides and fasting blood glucose. Patient groups did not differ significantly on weight lost (kg or %), or on the proportion of patients losing 10% of initial body weight.Discussion:In a community population, Met Syn responds to weight loss through a low-calorie lifestyle intervention; for some patients, however, the recommended 10% weight loss may not be enough for Met Syn remission.International Journal of Obesity (2009) 33, 144–150; doi:10.1038/ijo.2008.225; published online 18 November 2008
ACCESSION #
36035441

 

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