Interaction of BOP1, a protein for ribosome biogenesis, with EB1 in Giardia lamblia

Juri Kim; Seobo Sim; Tai-Soon Yong; Soon-Jung Park
November 2008
Parasitology Research;Nov2008, Vol. 103 Issue 6, p1459
Academic Journal
Abstract  A search for a protein(s) interacting with the block of proliferation 1 (Bop1) protein of Giardia lamblia led to the isolation of end binding (EB1) protein 1, a protein that is known to function as a microtubule (MT) plus-end-tracking protein in other organisms. Interaction between Bop1 and EB1 of G. lamblia was confirmed by co-immunoprecipitation of in vitro-synthesized Bop1 and EB1 proteins. This result suggests coordination between ribosome biogenesis and cell cycle-related processes such as mitosis.


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