Computational Analyses of TBC Protein Family in Eukaryotes

Xinjiao Gao; Changjiang Jin; Yu Xue; Xuebiao Yao
June 2008
Protein & Peptide Letters;Jun2008, Vol. 15 Issue 5, p505
Academic Journal
Tre-2/Bub2/Cdc16 domain-containing proteins (TBC proteins) participate in wide range cellular processes. With computational approaches, 137 non-redundant TBC proteins from five model organisms were identified and classified into 13 subfamilies base on molecular evolutionary tree. This phylogenetic analysis provides useful functional annotation of newly-identified TBC proteins and guides for further experimentation.


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