Lessons from Leptin's Molecular Biology: Potential Therapeutic Actions of Recombinant Leptin and Leptin-Related Compounds

G. Correia, M. L.; Haynes, W. G.
January 2007
Mini Reviews in Medicinal Chemistry;Jan2007, Vol. 7 Issue 1, p31
Academic Journal
Leptin, a peptide secreted by the white adipose tissue, circulates to the central nervous system and signals the status of body energy stores, regulating feeding behavior and energy balance. As human obesity is characterized by hyperleptinemia and leptin resistance, increasing leptin sensitivity is an attractive target for obesity treatment.


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