Clamping down on exocytosis

Rowan, Alison
August 2006
Nature Reviews Neuroscience;Aug2006, Vol. 7 Issue 8, p593
Academic Journal
The article discusses research being done on the role of complexin, along with exocytotic SNARE proteins, in calcium-mediated vesicle fusion. It references a study by C. G. Giraudo in the June 22, 2006 issue of "Science." Synaptotagmin, when added on its own or in the presence of calcium, had neither a blocking nor a stimulating effect on fusion, thus suggests that it is neither a clamp nor a fusion protein.


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