TITLE

New Human Embryonic Stem-Cell Lines to Be Made Available to Researchers

PUB. DATE
March 2004
SOURCE
Ascribe Newswire: Medicine;3/4/2004, p20
SOURCE TYPE
Newswire
DOC. TYPE
Article
ABSTRACT
Howard Hughes Medical Institute researchers at Harvard University announced today that they have derived 17 new human embryonic stem-cell lines. The new cell lines will be made available to researchers, although at this time United States policies prohibit the use of federal funds to investigate these cells. Human embryonic stem cells have the potential to yield treatments for several devastating human diseases, as well as to enhance understanding of human development. Studies of embryonic stem cells in several different organisms indicate that these cells have the capacity to give rise to nearly all of the cell types present in an adult organism.
ACCESSION #
12471629

 

Related Articles

  • Derivation of Embryonic Stem-Cell Lines from Human Blastocysts. Cowan, Chad A.; Klimanskaya, Irina; McMahon, Jill; Atienza, Jocelyn; Witmyer, Jeannine; Zucker, Jacob P.; Wang, Shunping; Morton, Cynthia C.; McMahon, Andrew P.; Powers, Doug; Melton, Douglas A. // New England Journal of Medicine;3/25/2004, Vol. 350 Issue 13, p1353 

    Reports on the development of 17 additional human embryonic stem cell lines. Frozen cleavage- and blastocyst-stage human embryos produced by in vitro fertilization for clinical purposes; How many were cultured to the blastcyst stage and allowed to re-expand; How the rest of the procedure went to...

  • Feeding hungry stem cells. Pedersen, Roger A. // Nature Biotechnology;Sep2002, Vol. 20 Issue 9, p882 

    Reports on research by M. Richards and colleagues demonstrating that two pre-existing human embryonic stem (HES) cell lines retained their undifferentiated state when cultured with human fetal fibroblasts. Theoretical and practical challenges posed by the dependence of HES cells on any feeder...

  • Agouti C57BL/6N embryonic stem cells for mouse genetic resources. Pettitt, Stephen J.; Qi Liang; Rairdan, Xin Y.; Moran, Jennifer L.; Prosser, Haydn M.; Beier, David R.; Lloyd, Kent C.; Bradley, Allan; Skarnes, William C. // Nature Methods;Jul2009, Vol. 6 Issue 7, p493 

    We report the characterization of a highly germline competent C57BL/6N mouse embryonic stem cell line, JM8. To simplify breeding schemes, the dominant agouti coat color gene was restored in JM8 cells by targeted repair of the C57BL/6 nonagouti mutation. These cells provide a robust foundation...

  • Uniform stable-isotope labeling in mammalian cells: formulation of a cost-effective culture medium. Egorova-Zachernyuk, Tatiana A.; Bosman, Giel J. C. G. M.; DeGrip, Willem J. // Applied Microbiology & Biotechnology;Jan2011, Vol. 89 Issue 2, p397 

    Uniform stable-isotope labeling of mammalian cells is achieved via a novel formulation of a serum-free cell culture medium that is based on stable-isotope-labeled autolysates and lipid extracts of various microbiological origin. Yeast autolysates allow complete replacement of individual amino...

  • Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency. Hotta, Akitsu; Cheung, Aaron Y. L.; Farra, Natalie; Vijayaragavan, Kausalia; Séguin, Cheryle A.; Draper, Jonathan S.; Pasceri, Peter; Maksakova, Irina A.; Mager, Dixie L.; Rossant, Janet; Bhatia, Mickie; Ellis, James // Nature Methods;May2009, Vol. 6 Issue 5, p370 

    Induced pluripotent stem (iPS) cells may be of use in regenerative medicine. However, the low efficiency of reprogramming is a major impediment to the generation of patient-specific iPS cell lines. Here we report the first selection system for the isolation of human iPS cells. We developed the...

  • Genomic instability of human embryonic stem cell lines using different passaging culture methods. Tosca, Lucie; Feraud, Olivier; Magniez, Aurélie; Bas, Cécile; Griscelli, Frank; Bennaceur-Griscelli, Annelise; Tachdjian, Gérard // Molecular Cytogenetics (17558166);2015, Vol. 8 Issue 1, p1 

    Background: Human embryonic stem cells exhibit genomic instability that can be related to culture duration or to the passaging methods used for cell dissociation. In order to study the impact of cell dissociation techniques on human embryonic stem cells genomic instability, we cultured H1 and H9...

  • Novel lines of Pax6-I- embryonic stem cells exhibit reduced neurogenic capacity without loss of viability. Quinn, Jane C; Molinek, Michael; Nowakowski, Tomasz J.; Mason, John O.; Price, David J. // BMC Neuroscience;2010, Vol. 11, p26 

    Background: Embryonic stem (ES) cells can differentiate into all cell types and have been used extensively to study factors affecting neuronal differentiation. ES cells containing mutations in known genes have the potential to provide useful in vitro models for the study of gene function during...

  • New Human Embryonic Stem-Cell Lines to Be Made Available to Researchers.  // Ascribe Newswire: Medicine;3/5/2004, p16 

    The article reports that researchers at Howard Hughes Medical Institute at Harvard University in Cambridge, Massachusetts have announced that they have derived 17 new human embryonic stem-cell lines. The new cell lines will be made available to researchers, although at this time U.S. policies...

  • Stem Cell Therapeutics: Exploring Newer Alternatives to Human Embryonic Stem Cells. Garg, Abhishek D. // Internet Journal of Health;2008, Vol. 8 Issue 1, p16 

    Stem cells therapeutics has come a long way since stem cells and their potential was discovered for the first time. Intense research into cellular biology of stem cells has revealed that they possess immense potential for curing many human diseases. Research done in last couple of decades...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics