TITLE

Free thyroxine in needle washout after fine needle aspiration biopsy of toxic thyroid nodules

AUTHOR(S)
Raikov, Nikolai; Nonchev, Boyan; Chaushev, Borislav; Vjagova, Diyana; Todorov, Svetoslav; Bocheva, Yana; Malceva, Daniela; Vicheva, Snejinka; Raikova, Asyia; Argatska, Antoaneta; Raikov, Miroslav
PUB. DATE
January 2016
SOURCE
Nuclear Medicine Review;2016, Vol. 19 Issue 1, p18
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The main diagnostic tool for toxic adenomas (TA) is radionuclide imaging indicated in patients with evidence of thyroid nodules in combination with thyrotoxic syndrome. Thyroid ultrasound and fine-needle aspiration biopsy (FNAB) are widely used for the valuation of thyroid masses. There is no literature data concerning the utility of FNAB and related tests for the diagnosis of hyperfunctioning thyroid nodules. The purpose of this study is to determine the levels of free thyroxine (FT4) in the needle washout after FNAB of hot thyroid nodules. The results of our study show that the FT4 levels in needle washout from TA were significantly higher than the surrounding parenchyma and correlated with the hormonal changes in patients with thyroid hyperfunctioning nodules. Further studies on a large number of patients are needed to refine the diagnostic value of this method and evaluate its importance in quantitative risk assessment of thyroid autonomy.
ACCESSION #
112820087

 

Related Articles

  • The role of repeat fine needle aspiration in the management of indeterminate thyroid nodules. Jooya, Alborz; Saliba, Joe; Blackburn, Audrey; Tamilia, Michael; Hier, Michael P.; Mlynarek, Alex; Forest, Véronique-Isabelle; Rochon, Louise; Florea, Anca; Hangjun Wang; Payne, Richard J. // Journal of Otolaryngology -- Head & Neck Surgery;10/18/2016, Vol. 45, p1 

    Background: Management decisions are not straightforward when the Ultrasound Guided Fine Needle Aspiration (USFNA) demonstrates a Bethesda score of either category III or IV, and a diagnostic hemi-thyroidectomy or a repeat USFNA (r-USFNA) could be performed. The aim of this study is to assess...

  • New Test May Diagnose Thyroid Cancer Without Surgery. McBride, Deborah // ONS Connect;Oct2012, Vol. 27 Issue 10, p8 

    The article focuses on the study by E.K. Alexander and colleagues which shows that fine-needle aspiration (FNA) is a useful tool for diagnosing thyroid cancer and can eliminate the need for diagnostic surgery.

  • Insight to neoplastic thyroid lesions by fine needle aspiration cytology. Rangaswamy, M; Narendra, Kl; Patel, S; Gururajprasad, C; Manjunath, Gv // Journal of Cytology;Jan-Mar2013, Vol. 30 Issue 1, p23 

    Background: Fine needle aspiration cytology (FNAC) is a valuable adjunct to pre‑operative screening in the diagnosis of thyroid nodules, and in most cases, it can distinguish between benign and malignant lesions. Aim: To study the cytology of neoplastic thyroid lesions to minimize...

  • Malignancy Rate in Thyroid Nodules Classified as Bethesda Category III (AUS/FLUS): Is There a Correct Answer? Heller, Keith S. // Thyroid;May2014, Vol. 24 Issue 5, p787 

    The author discusses application of thyroid fine-needle aspiration (FNA) to evaluate the thyroid nodules, and mentions the Bethesda System for Reporting Thyroid Cytopathology which permits effective communication among clinicians. He also discusses a study conducted by researchers Allen Ho and...

  • Isolated intrathyroidal metastasis revealing an occult lung adenocarcinoma. Pasricha, Sunil; Gandhi, Jatin S.; Mehta, Anurag; Gupta, Gurudutt // Journal of Cytology;Jan-Mar2012, Vol. 29 Issue 1, p92 

    Thyroid gland is an uncommon site of tumor metastasis inspite of rich vascular supply. Most of the cases are picked up after the diagnosis or during the work up for the primary. Unexpected involvement of thyroid gland as the first presenting sign in a primary lung adenocarcinoma is an extremely...

  • Diagnosis of carcinomas of extrathyroidal origin with fine needle aspiration cytology of the thyroid: An experience from a tertiary care center in South India. Sreedharanunni, Sreejesh; Vidyadharan, Geeta; Jojo, Annie // Journal of Cytology;Apr2014, Vol. 31 Issue 2, p108 

    Intrathyroidal metastasis and direct extension of extrathyroidal malignancies can present with palpable thyroid nodules or may be detected as suspicious nodules in a thyroid scan. They can lead to diagnostic difficulty in fine needle aspiration cytology (FNAC) of the thyroid, especially in the...

  • Poorly differentiated (insular) thyroid carcinoma arising in a longstanding colloid goitre: A cytological dilemma. Kini, Hema; Nirupama, M.; Rau, Aarathi R.; Gupta, Sumit; Augustine, Alfred // Journal of Cytology;Jan-Mar2012, Vol. 29 Issue 1, p97 

    Poorly differentiated (insular) thyroid carcinoma (PDITC) is an uncommon thyroglobulin producing neoplasm intermediate in aggressiveness between well-differentiated carcinomas of follicular cell origin and undifferentiated anaplastic carcinoma. Its cytomorphological recognition is essential for...

  • Follicular Adenoma and Carcinoma of the Thyroid Gland. Mchenry, Christopher R.; Phitayakorn, Roy // Oncologist;May2011, Vol. 16 Issue 5, p585 

    Follicular neoplasms of the thyroid gland include benign follicular adenoma and follicular carcinoma. Currently, a follicular carcinoma cannot be distinguished from a follicular adenoma based on cytologic, sonographic, or clinical features alone. The pathogenesis of follicular carcinoma may be...

  • Primary Benign and Malignant Thyroid Neoplasms With Signet Ring Cells: Cytologic, Histologic, and Molecular Features. Farhat, Nada A.; Onenerk, Ayse M.; Krane, Jeffrey F.; Dias-Santagata, Dora; Sadow, Peter M.; Faquin, William C. // American Journal of Clinical Pathology;Sep2017, Vol. 148 Issue 3, p251 

    Objectives: Signet ring cells (SRCs) can be seen in a variety of thyroid tumors and can pose a diagnostic pitfall on cytology. This study describes the cytologic, histomorphologic, and molecular aspects of a cohort of primary thyroid tumors with SRCs.Methods: A search...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics