TITLE

Crystallography of Membrane Proteins, Major Targets in Drug Design

AUTHOR(S)
J. Wouters
PUB. DATE
August 2003
SOURCE
Mini Reviews in Medicinal Chemistry;Aug2003, Vol. 3 Issue 5, p439
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Protein crystallography has the potential to accelerate drug discovery greatly. High-resolution structures of membrane proteins of pharmaceutical interest open new perspectives in drug design. Recent structural data obtained for cyclooxygenases, monoamine oxidase, squalene cyclase, rhodopsine, porins, aquaporins, and ABC transporters are presented and briefly discussed.
ACCESSION #
10481083

 

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