TITLE

Response to Disodium Etidronate Treatment in Three Siblings with Pulmonary Alveolar Microlithiasis

AUTHOR(S)
Cakir, Erkan; Gedik, Ahmet Hakan; Özdemir, Ali; Buyukpınarbasili, Nur; Bilgin, Mehmet; Ozgen, Ilker Tolga
PUB. DATE
June 2015
SOURCE
Respiration;Jun2015, Vol. 89 Issue 6, p583
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Pulmonary alveolar microlithiasis (PAM) is a rare chronic genetic lung disease in childhood with no proven therapy. It is characterized by the deposition of calcium phosphate microliths within the alveolar air spaces. The effect of disodium etidronate (DE) treatment on PAM is controversial. We report 3 siblings (an 11-year-old boy and 4-year-old twin girls) with PAM diagnosed by chest X-ray, thoracic high-resolution computed tomography, technetium-99m bone scan and bronchoalveolar lavage fluid findings. After the administration of DE (200 mg/day) for a 1-year period, 2 siblings showed radiological improvement, while 1 sibling did not. No drug side effects were observed within the treatment period. © 2015 S. Karger AG, Basel
ACCESSION #
103427987

 

Related Articles

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics