TITLE

Inflamación y obesidad (lipoinflamación)

AUTHOR(S)
Izaola, Olatz; de Luis, Daniel; Sajoux, Ignacio; Carles Domingo, Joan; Vidal, Montserrat
PUB. DATE
June 2015
SOURCE
Nutricion Hospitalaria;jun2015, Vol. 31 Issue 6, p2352
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Obesity is a chronic disease with multiple origins. It is a widespread global phenomenon carrying potentially serious complications which requires a multidisciplinary approach due to the significant clinical repercussions and elevated health costs associated with the disease. The most recent evidence indicates that it shares a common characteristic with other prevalent, difficult-to-treat pathologies: chronic, low-grade inflammation which perpetuates the disease and is associated with multiple complications. The current interest in lipoinflammation or chronic inflammation associated with obesity derives from an understanding of the alterations and remodelling that occurs in the adipose tissue, with the participation of multiple factors and elements throughout the process. Recent research highlights the importance of some of these molecules, called pro-resolving mediators, as possible therapeutic targets in the treatment of obesity. This article reviews the evidence published on the mechanisms that regulate the adipose tissue remodeling process and lipoinflammation both in obesity and in the mediators that are directly involved in the appearance and resolution of the inflammatory process.
ACCESSION #
103142394

 

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